My Night with Reg is a 1996 British film adapted from the Kevin Elyot play of the same title, and directed by Roger Michell.

Entirely set among London's gay community in the mid-1980s against the background of the mounting AIDS crisis, My Night with Reg follows the ups and downs of a circle of gay friends over a period of several years. One of the group, the Reg mentioned in the title, is not a character in the play but the whole plot revolves around his apparent promiscuity and the chain reaction of deception and betrayal set off by it.