Indiana Jones and the Kingdom of the Crystal Skull is a 2008 American action adventure film directed by Steven Spielberg from a screenplay by David Koepp, based on a story by George Lucas and Jeff Nathanson. It is the fourth installment in the Indiana Jones film series and a sequel to Indiana Jones and the Last Crusade (1989). Set in 1957, it pits Indiana Jones (Harrison Ford) against Soviet KGB agents led by Irina Spalko (Cate Blanchett) searching for a telepathic crystal skull located in Peru.

Jones is aided by his former lover, Marion Ravenwood (Karen Allen), and their son, Mutt Williams (Shia LaBeouf). Ray Winstone, John Hurt, and Jim Broadbent are also part of the supporting cast.

Jeb Stuart, Jeffrey Boam, Frank Darabont, Lucas, and Nathanson wrote drafts before Koepp's script satisfied the producers. The filmmakers intended to pay tribute to the science fiction B movies in the 1950s. Shooting began on June 18, 2007, at various locations in New Mexico, New Haven, Connecticut, Hawaii, and Fresno, California, as well as on sound stages in Los Angeles. To maintain aesthetic continuity with the previous films, the crew relied on traditional stunt work instead of computer-generated stunt doubles, and cinematographer Janusz Kamiński studied Douglas Slocombe's style from the previous films.

Indiana Jones and the Kingdom of the Crystal Skull had its premiere at the 61st Cannes Film Festival on May 18, 2008, and was released in the United States on May 22, by Paramount Pictures. It received generally positive reviews from critics but mixed responses from audiences. The film was also a financial success, grossing over $786 million worldwide which makes it the franchise's highest-grossing film (when not adjusted for inflation) as well as the second-highest-grossing film of 2008.

Indiana Jones and the Kingdom of the Crystal Skull is the last film in the Indiana Jones franchise to be distributed by Paramount, as the Walt Disney Studios acquired rights to future films following the parent company's acquisition of Lucasfilm in October 2012, with Paramount still retaining the rights to the original four films and receiving "financial participation" from any additional properties. It is also the last film in the series for which Spielberg and Lucas are credited with the direction and story, respectively. A sequel concluding the saga, titled Indiana Jones and the Dial of Destiny, was released on June 30, 2023.