Resident Evil: Extinction is a 2007 action horror film directed by Russell Mulcahy and written by Paul W. S. Anderson. A direct sequel to Resident Evil: Apocalypse (2004), it is the third installment in the Resident Evil film series, which is loosely based on the Capcom survival horror video game series of the same name. The film follows the heroine Alice, along with a group of survivors from Raccoon City, as they attempt to travel across the Mojave desert wilderness to Alaska and escape a zombie apocalypse.

In November 2005, Screen Gems gained the rights for the third installment in the franchise, which was then subtitled Extinction. Anderson returned as a writer, and filming took place in Mexico with Mulcahy as the director.

Resident Evil: Extinction was released in the United States on September 21, 2007, and was released in the United Kingdom on October 12, 2007, by Sony Pictures Releasing. The DVD and Blu-ray versions were released in North America on January 1, 2008. Like its predecessors, the film received generally negative reviews from critics but was a box office success, grossing $147.7 million worldwide against a $45 million budget. A fourth film, Resident Evil: Afterlife, was released in 2010.