Resident Evil: Retribution is a 2012 action horror film written and directed by Paul W. S. Anderson. A sequel to Resident Evil: Afterlife (2010), it is the fifth installment in the Resident Evil film series, loosely based on the video game franchise of the same name. It is also the third to be written and directed by Anderson after the first film and Afterlife. The film focuses on Alice (Milla Jovovich) captured by the Umbrella Corporation, forcing her to make her escape from an underwater facility in the Extreme North, used for testing the T-virus.

Written and directed by Anderson, Retribution was planned to be filmed back to back with the sixth installment, but Anderson decided to focus on the fifth film. Filming took place in Toronto, Ontario from mid-October to December 23, 2011. The film has many returning actors and characters, along with new characters from the video games not featured in the previous films, including Leon S. Kennedy, Ada Wong, and Barry Burton.

The film was released in 2D, 3D and IMAX 3D to box-office success, grossing over $240 million worldwide, but received generally negative reviews from critics, who criticized the characters, plot and acting, while praising the 3D, visual effects and fight choreography. The DVD and Blu-ray for the film was released on December 21, 2012, in the U.S. A sixth film, Resident Evil: The Final Chapter, was released in 2016.