The Dr. Oz Show (or simply Oz) is an American syndicated daytime television talk show, hosted by Mehmet Oz, that aired between September 14, 2009, and January 14, 2022. Each episode features segments on health, wellness, and medical information, sometimes including true crime stories and celebrity interviews. It was co-produced by Oprah Winfrey's Harpo Productions/Harpo Studios and OzWorks LLC/Oz Media in association with Sony Pictures Television.

The Dr. Oz Show received nine Daytime Emmy Awards during its run, five for Outstanding Informative Talk Show and four for Outstanding Informative Talk Show Host, as well as criticism for some of its subject matter.

After Oz's November 2021 announcement that he would run as a Republican for the U.S. Senate seat in Pennsylvania, the show ceased production and aired its final episode on Friday, January 14, 2022. A food-themed spin-off talk show, The Good Dish, filled the timeslot on most stations from January 17 through the end of the 2021–22 television season, with its final episode airing May 25, 2022.