The Fall and Rise of Reginald Perrin is a British sitcom starring Leonard Rossiter in the title role. Three series were produced from 1976 to 1979, based on a series of novels written by David Nobbs. Nobbs adapted the screenplay for the first series from the first novel. Some of its subplots were considered too dark or risqué for television and were toned down or omitted. A fourth series, The Legacy of Reginald Perrin, also written by Nobbs, followed in 1996.

The story concerns a middle-aged middle manager, Reginald "Reggie" Perrin, who is revealed in the first series to be aged 46, and is driven to bizarre behaviour by the pointlessness of his job at Sunshine Desserts. The sitcom proved to be a subversion of others of the era, which were often based on bland, middle-class suburban family life.

The first novel in the series, The Death of Reginald Perrin, was published in 1975. Later editions were retitled to match the title of the television series. The Return of Reginald Perrin (1977) and The Better World of Reginald Perrin (1978) were written by Nobbs to be adapted for the second and third television series; Rossiter did not want to take the series forward unless it continued to be grounded in novels.

A new dramatisation of the original novels by Jon Canter, without the complications introduced in the TV series, was broadcast on BBC Radio Four in November 2022.