Los misterios de Laura (transl. The Mysteries of Laura) is a prime-time Spanish police procedural comedy-drama television series that was broadcast on La 1 of Televisión Española from 2009 to 2014, followed by three television movies broadcast in 2022 and 2023. It stars María Pujalte as Laura Lebrel, a police detective with a disorganized personal and professional life, and a casual and pleasant personality, but with a great nose and intuition for solving intriguing cases.

The series, that was initially going to be named Madres y detectives (transl. Mothers & Detectives), premiered on 27 July 2009 with huge success, surpassing the rival of the night CSI: Crime Scene Investigation.

The series has been adapted in Italy as I misteri di Laura starring Carlotta Natoli, the Netherlands as Rechercheur Ria starring Ellen Pieters and Russia as Mama-detektiv starring Inga Strelkova-Oboldina. On 8 May 2014 American network NBC announced an American adaptation, titled The Mysteries of Laura and starring Debra Messing.