This American Life is an American television series based on the radio program of the same name. Like the radio program, the series is hosted by Ira Glass. The series premiered on March 22, 2007. Two seasons of the show aired on Showtime. The second season finale aired on September 3, 2008, and Showtime aired one final episode in May 2009.

In September 2009, Glass announced that he and the other creators of the show had "asked to be taken off TV", largely in part to the difficult schedule required to produce a television program. He went on to state that the show is officially "on hiatus", but would like to do a television special at some point in the future. From January 10 to April 4, 2011, Current TV re-aired the series in its entirety.