Family Affair is an American sitcom starring Brian Keith and Sebastian Cabot that aired on CBS from September 12, 1966, to March 4, 1971. The series explored the trials of well-to-do engineer and bachelor Bill Davis (Keith) as he attempted to raise his brother's orphaned children in his luxury New York City apartment. Davis' traditional English gentleman's gentleman, Mr. Giles French (Cabot), also had adjustments to make as he became saddled with the responsibility of caring for 15-year-old Cissy (Kathy Garver) and the six-year-old twins, Jody (Johnny Whitaker) and Buffy (Anissa Jones).

Family Affair ran for 138 episodes in five seasons. The show was created and produced by Edmund Hartmann and Don Fedderson, also known for My Three Sons and The Millionaire.