My 600-lb Life is an American reality television series that has aired on the TLC television network since 2012. Each episode follows a year in the life of morbidly obese individuals, who usually begin the episode weighing at least 600 pounds (270 kg), and documents their attempts to reduce their weight to a healthy level. Update episodes, called "Where Are They Now?", feature one or more previous patients, picking up a year or more after their original episodes aired.

Patients are placed under the care of Houston surgeon Younan Nowzaradan (often referred to as "Dr. Now"), who first has them attempt losing weight on their own by following a strict diet, and then depending on the patient's progress may offer gastric bypass surgery or sleeve gastrectomy to further assist in weight loss.