The Sparticle Mystery is a British science fiction television series written and created by Alison Hume and produced by Sparticles Productions for CBBC. The series follows a group of ten children in modern Britain, where an experiment at a Large Hadron Collider-like facility, the Sparticle Project, goes wrong, sending anybody aged 15 and over into a parallel dimension at exactly 11:11 am. The children travel to the Sparticle Project in an attempt to bring back the adults and re-align the two dimensions.

The series, which had a budget of £3 million, was filmed in and around Bristol, with the final episode filmed at the ISIS neutron source particle accelerators, near Didcot. Series 2 was extremely popular, with over 2 million hits on BBC iPlayer. Series 3 regularly topped the BARB top ten children's shows during transmission. In general, the series has received mixed to positive reception, with a score of 7.3 on IMDb.

The programme, which stars Annette Badland as Doomsday Dora/Holodora, has similar themes to both the 1975 TV series The Changes and the Gone series, and has many similarities to The Tribe; however, it is noted for its difference in that the children desire to bring back the adults. The second series of The Sparticle Mystery was filmed across Yorkshire in July- September 2012 and broadcast in 2013. A third series was filmed in 2014 in and around Belfast, Northern Ireland with the support of Northern Ireland Screen, and the first episode was broadcast on 5 January 2015. The third and final series ended on 30 March 2015. Video-on-demand rights to The Sparticle Mystery were acquired by Amazon UK Prime in 2015 and Series 1 & 2 were available to watch until 2017. In the US, Seasons 1 and 2 are available from Netflix. Series 3 is available on the BBC Store.

From 2019, The Sparticle Mystery Series 1 was available to watch on BBC iPlayer in the UK, but as of 2023 it is not.