Space Cases is a Canadian science fiction television series that aired on Nickelodeon for two seasons. Created by Peter David and Bill Mumy, it premiered on March 2, 1996, and ended on January 27, 1997, with reruns until 1998. Space Cases aired for a time on Nickelodeon's Saturday night block of shows known as SNICK, and on Nickelodeon UK, with reruns on Family and TVOntario in Canada.

A Space Cases episode aired on TeenNick in the US as part of its The '90s Are All That block on the night of October 14, 2011, for the block's U Pick with Stick line-up, and again on December 27, 2011, for Party Like It's the '90s. Space Cases returned once again on the night of January 1, 2016, on TeenNick during the new The Splat programming block but has not aired since; the first four episodes of Season One were aired.

The show's premise revolves around a group of misfit students and two adults who are stranded far from home aboard an alien ship. Their attempts at journeying back see many dangerous adventures and controversies, with some occasionally more mature themes.