Resident Evil is a 2002 action horror film written and directed by Paul W. S. Anderson. The film stars Milla Jovovich, Michelle Rodriguez, Eric Mabius, James Purefoy, Martin Crewes, and Colin Salmon. It is the first installment in the Resident Evil film series, which is loosely based on the video game series of the same name. Borrowing elements from the video games Resident Evil and Resident Evil 2, the film follows amnesiac heroine Alice and a band of Umbrella Corporation commandos as they attempt to contain the outbreak of the T-virus at a secret underground facility.

German studio Constantin Film bought the rights to adapt the series in live-action in January 1997. Several writers and filmmakers, such as Alan B. McElroy, George A. Romero and Jamie Blanks, were initially hired to direct and write the film, but their scripts were rejected. In 2000, Anderson was announced as writer and director. Developed as a prequel set in the same continuity as the video game series, the film was initially titled Resident Evil: Ground Zero, but was retitled after the September 11 attacks. Cast was announced in early 2001 and principal photography commenced in March 2001 in Berlin.

Resident Evil was theatrically released in Germany on March 12, 2002, by Constantin Film Verleih, and in the United Kingdom on July 12, 2002, by Pathé Distribution. It received generally negative reviews from critics but grossed $103 million worldwide against a production budget of $33 million. It was followed by five sequels establishing their own continuity: Apocalypse (2004), Extinction (2007), Afterlife (2010), Retribution (2012), and The Final Chapter (2016).