YOLO is an adult animated television series created by Michael Cusack for Cartoon Network's nighttime programming block Adult Swim, and streaming in Australia on Stan as an exclusive. The series is loosely adaptated from Cusack's web series of the same name. The first season, entitled YOLO: Crystal Fantasy premiered on August 10, 2020; the pilot was aired on April 1, 2020 as a part of Adult Swim's annual April Fools' Day event alongside another project of Cusack's, Smiling Friends. A second season titled YOLO: Silver Destiny was slated to air on January 16, 2023 on Adult Swim but was delayed to January 23, 2023. On October 12, 2023, it was announced that the series was renewed for a third season titled YOLO: Rainbow Trinity which premiered on March 9, 2025.

The series follows the adventures of friends Rachel and Sarah as they travel through Australia.