Otome Yōkai Zakuro (おとめ妖怪 ざくろ, lit. "Maiden Spirit Zakuro") is a Japanese manga series written and illustrated by Lily Hoshino. It has been serialized in Gentosha's seinen manga magazine Comic Birz since November 2006; its chapters have been collected in ten tankōbon volumes as of March 2015. The series was put on hiatus in October 2016 and resumed in January 2024. A 13-episode anime television series adaptation produced by J.C.Staff and directed by Chiaki Kon aired from October to December 2010.