Oh Yeah! Cartoons is an American animated anthology series that aired on Nickelodeon. Created by Fred Seibert, it was produced by Frederator Incorporated and Nickelodeon Animation Studio, running as part of Nickelodeon's Nicktoons lineup. In the show's first season, it was hosted by a variety of schoolchildren, and the second season was hosted by Kenan Thompson of All That and Kenan & Kel, and later Josh Server of All That in the third and final season. Bill Burnett composed the show's theme music.

In terms of total volume, Oh Yeah! Cartoons remains TV's biggest animation development program ever. Giving several dozen filmmakers the opportunity to create 96 seven-minute cartoons, the series eventually yielded three dedicated half-hour spin-off shows produced by Frederator: The Fairly OddParents, ChalkZone, and My Life as a Teenage Robot.

Nickelodeon's Oh Yeah! featured in its first season a total of 39 brand new seven-minute cartoons, surpassing the number of new cartoons and characters on any other single network. In its full run, Oh Yeah! Cartoons featured and produced 96 cartoons.

Many of the animated shorts were created by cartoonists who later became more prominent, including Bob Boyle, Bill Burnett, Jaime Diaz, Greg Emison, John Eng, Thomas R. Fitzgerald, John Fountain, Antoine Guilbaud, Butch Hartman, Larry Huber, Ken Kessel, Alex Kirwan, Steve Marmel, Seth MacFarlane, Zac Moncrief, Carlos Ramos, Rob Renzetti, C. Miles Thompson, Byron Vaughns, Pat Ventura, Vincent Waller, and Dave Wasson.

Many of its animators featured had worked two years earlier on Cartoon Network's What a Cartoon!, produced in the same concept by Hanna-Barbera and Cartoon Network Studios, which was also created by Seibert while he was president of that historical studio. Seibert created Random! Cartoons as a sequel anthology. While originally intended as a fourth season of Oh Yeah! Cartoons, it ended up being made as another show. Random! Cartoons aired on Nicktoons from 2008 to 2009.