Andy Richter Controls the Universe is an American sitcom created by Victor Fresco that originally aired on Fox from March 19, 2002, to January 12, 2003. The series was Andy Richter's first starring role after leaving NBC's Late Night with Conan O'Brien in 2000, and centers around Richter's eponymous character, a writer living in Chicago who works at a fictional company called Pickering Industries. The show was a joint production of Garfield Grove Productions and 20th Century Fox Television in association with Paramount Television.

Filmed in Los Angeles, California using a single-camera setup, the series was developed after Richter expressed interest in expanding his acting repertoire beyond his previous sidekick role on late-night television. It utilizes a unique narrative style, blending nonlinear storytelling with the unreliable narrator trope. The show features an ensemble cast, including Paget Brewster, Irene Molloy, Jonathan Slavin, and James Patrick Stuart.

Andy Richter Controls the Universe received critical acclaim for its inventive humor and writing, drawing comparisons to other successful Fox comedies such as The Simpsons. Despite positive reviews, the series suffered from low ratings, leading to its cancellation after two mid-season runs. The series has since gained a cult following and is regarded as a forerunner to the wave of single-camera comedies that followed, such as Arrested Development.