Cancer: The Emperor of All Maladies is a 2015 American documentary film produced and directed by Barak Goodman and executive produced by Ken Burns. The film, in three episodes of two hours each, is based on the Pulitzer Prize–winning 2010 book The Emperor of All Maladies: A Biography of Cancer, by Siddhartha Mukherjee, and describes the history of cancer and cancer treatments, particularly in the United States.

The film is narrated by Edward Herrmann, who was himself suffering from terminal brain cancer at the time of its production. He died on December 31, 2014, three months before the film's release, making the series his final performance.